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KMID : 0043320080310101275
Archives of Pharmacal Research
2008 Volume.31 No. 10 p.1275 ~ p.1279
Anti-angiogenic, Anti-inflammatory and Anti-nociceptive Activities of Vanillyl Alcohol
Park Eun-Hee

Lim Chang-Jin

Chong Hyun-Ju
Abstract
Vanillyl alcohol displayed a significant inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. Vanillyl alcohol was also shown to contain anti-inflammatory activity using acetic acid-induced permeability and carrageenan-induced air pouch models in mice. Anti-nociceptive activity of vanillyl alcohol was also assessed using acetic acid-induced writhing test in mice. Taken together, vanillyl alcohol possesses anti-angiogenic, anti-inflammatory, and anti-nociceptive activities, which may be partly responsible for pharmacological efficacies of several folkloric medicines containing vanillyl alcohol.
KEYWORD
Vanillyl alcohol, Anti-inflammatory, Anti-angiogenic, Anti-nociceptive
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